Chronic Kidney Disease

Disease State Hub

Clinical Insights

Expert Q&A

05/10/2023

In this Q&A, Ping Liu, PhD, and Pietro Ravani, MD, PhD, answer our questions about the diagnosis and management of chronic kidney disease (CKD) and discuss how the current definition of CKD does not...

05/10/2023

podcast

Social Determinants of Chronic Kidney Disease

11/22/2022

In this podcast, James Matera, DO, speaks about the impact of poverty and food insecurity on chronic kidney disease (CKD), including an update to a study funded by the National Institutes of Health on food...

11/22/2022

Management

Managing Chronic Kidney Disease in Primary Care

11/18/2022

In this video, James J. Matera, DO, speaks about the take-home messages from his session "A Primary Care Approach to CKD Management" at our Practical Updates in Primary Care 2022 Virtual Series,...

11/18/2022

Chronic Kidney Disease

Monitoring and Following Patients With Chronic Kidney Disease

10/06/2022

In this podcast, Kim Zuber, PA-C, explains the current gold standard for monitoring and following patients with chronic kidney disease and what has been done to ensure standardized laboratory monitoring for...

10/06/2022

Video

Preview: The Primary Care Approach to the Patient With Chronic Kidney Disease

04/22/2022

In this video, James J. Matera, DO, provides a preview of his session "A Primary Care Approach to CKD Management" at our Practical Updates in Primary Care 2022 Virtual Series on May 12, including the...

04/22/2022

Kidney Disease

Diet Planning Guide: Nutritional Considerations in CKD and ESRD

01/31/2022

James J. Matera, DO, from CentraState Medical Center in New Jersey, and Jamie Miller, MS, RD, from Saint Barnabas Medical Center in New Jersey, discuss key dietary needs among patients with chronic kidney...

01/31/2022

Review

Kidney Disease Diet for Patients Not on Dialysis

03/07/2018

Approximately 14% of people in the United States have some stage of kidney disease.

03/07/2018

Chronic Kidney Disease Snapshot

Reviewed by James Matera, DO

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CKD is the progressive loss of kidney function, which filters waste products from the blood and maintains fluid balance by producing urine. Advanced CKD can cause dangerous levels of fluid, electolytes, and nitrogenous waste to build up in the body.

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CKD may lead to high blood pressure, heart disease, stroke, and early death. CKD can also be called chronic kidney failure or chronic renal insufficiency. CKD is classified into 5 levels, based on the estimated glomerular filtration rate (eGFR).

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Nephrologist, Nutritionist, Primary Care Physician, Transplant Surgeon

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nausea, vomiting, loss of appetite, fatigue and weakness, sleep problems, urinating more or less, decreased mental sharpness, muscle cramps, swelling of feet and ankles, dry, itchy skin, hypertension, shortness of breath, chest pain

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Serum Creatinine Blood Test: Creatinine is a waste product from the normal use of muscles in the body. The serum creatinine level increases if the kidneys are not functioning properly. Creatinine level > 1.2 for women and > 1.4 for men is considered elevated.

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eGFR measures kidney function. Creatinine level, age, and sex are used to calculate eGFR. As kidney disease progresses, eGFR decreases. eGFR <60 ml/min is generally below normal limits and <15 ml/min is generally considered advanced kidney failure.

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Blood urea nitrogen (BUN) measures the amount of urea nitrogen in the blood, which is a waste product that the body creates from breaking down protein in food. Healthy kidneys filter urea nitrogen out of the blood, and it exits the body through urine.

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BUN (continued): Normal levels of urea nitrogen depend on age and other factors and generally range from 7 to 20. As kidney disease progresses, the BUN level increases.

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CKD is slightly more common in women compared with men and more common in Black adults compared with White or Asian adults.

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38% of people aged 65 years or older have CKD, 12% of people aged 45 to 64 years have CKD, and 6% of people aged 18 to 44 years have CKD.

Research Summaries

Research Summary

Large Case Series Identifies Key Clinical, Pathological Characteristics of Patients With Oxalate Nephropathy

05/24/2024

Anthony Calabro, MA

Oxalate nephropathy is a commonly underrecognized cause of chronic kidney disease and end-stage kidney disease with multiple etiologies, including primary hyperoxaluria, enteric hyperoxaluria, or ingestion...

05/24/2024

RESEARCH SUMMARY

Study Points to Renal Dysfunction as a Potential Risk Factor for Relapse, Biomarker in Patients With NMOSD

05/20/2024

Anthony Calabro, MA

Researchers set out to determine whether renal function could be used as both a predictor of relapse risk for patients with their first onset of aquaporin-4 (AQP4)-immunoglobulin G (IgG)-seropositive...

05/20/2024

research summary

Urine, Plasma Oxalate in Children With Primary Hyperoxaluria Type 1

02/28/2024

Leigh Precopio

Individuals with primary hyperoxaluria type 1 are at an increased risk of urinary stone disease, nephrocalcinosis, and chronic kidney disease due to increased hepatic oxalate production. Researchers...

02/28/2024

FDA ALERT

FDA Approves Nedosiran for Patients 9 Years of Age and Older With Primary Hyperoxaluria Type 1

01/29/2024

Anthony Calabro, MA

The once-monthly RNA interference injection medication received FDA approval based on results from the phase II PHYOX2 clinical trial and phase III PHYOX3 extension study.

01/29/2024

roundtable wrap-up

roundtable wrap-up

Collaboration as a Tool in Managing Nutrition for Patients With CKD

07/05/2023

Did you watch our Multidisciplinary Roundtable on managing nutrition in patients with chronic kidney disease? Here are some highlights that you may have missed. 

07/05/2023

August 2024

Current Issue

August 2024

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