Study Details Antibiotic Resistance Trends in Ocular Infections
Antimicrobial resistance among ocular staphylococci and Streptococcus pneumonia have remained high or increased over the last decade, according to a recent study.
The results were presented at the American Academy of Ophthalmology 2016 annual meeting.
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To examine antibiotic resistance profiles and resistance over time, the researchers analyzed ocular isolates collected from 1229 participants in the TRUST (2006-2008) and 4226 participants in the ARMOR (2009-2015) nationwide surveys.
Overall, 38% of 1991 S. aureus were resistant to methicillin, 50% of 1456 coagulase-negative staphylococci were resistant to methicillin, and 34% of 789 S. pneumonia isolates were resistant to azithromycin.
Although antibiotic resistance has remained stable within the last 10 years, a small but significant decrease was found among S. aureus resistance to oxacillin, ciprofloxacin, and tobramycin, and among coagulase-negative staphylococci resistance to oxacillin and ciprofloxacin.
However, S. pneumonia resistance to azithromycin doubled from 22% to 44% and resistance to oral penicillin increased from 18% to 33%.
“In the last decade, antimicrobial susceptibility rates among bacteria collected during ocular surveillance programs have remained relatively stable, with few exceptions,” the researchers concluded. “Additional longitudinal data are needed to determine whether those trends persist.”
—Amanda Balbi
Reference:
Asbell PA, Sanfilippo CM, DeCory HH. Antimicrobial susceptibility in ocular isolates: from TRUST to ARMOR. Paper presented at: American Academy of Ophthalmology (AAO) 2016; October 15-18, 2016; Chicago, IL. https://aao.apprisor.org/apsAuthors.cfm. Accessed October 21, 2016.