IBD Prevalence Has Stabilized, Decreased in Western World
The incidence of inflammatory bowel disease (IBD) has stabilized and decreased in North America, Europe, and Oceania, according to a recent systematic review. However, the prevalence of IBD has risen in newly industrialized countries outside of the Western world, including Brazil and Taiwan.
Findings from the review were presented by Dr Gilaad Kaplan on October 16, 2017, at the World Congress of Gastroenterology at the American College of Gastroenterology (ACG) 2017.
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IBD has evolved into a global disease in the 21st century, but little is known about its current incidence in different regions of the world.
For their review, Dr Kaplan and colleagues screened 11,170 reports and identified 226 full-text reviews and 113 incidence studies on Celiac disease (CD) or ulcerative colitis (UC) from inception to December 31, 2016.
The incidence of CD and UC from 1990 to 2016 was determined via choropleth maps. Temporal trend analyses were conducted with Poisson regression, and results were reported as annual percent change with 95% confidence intervals.
Results indicated that overall, 70% of studies on CD and 83.3% of studies on UC had shown stable or decreasing prevalence of IBD in North America, Europe, and Oceania since 1990. However, the incidence of IBD has risen in newly industrialized countries outside of the Western world, including Brazil and Taiwan.
“This systematic review provides a comprehensive global overview of the incidence of IBD over the past generation,” the researchers concluded.
“We have observed a paradigm shift in the epidemiology of IBD. Since 1990, the incidence of IBD has stabilized in the Western world. In contrast, newly industrialized countries are showing rising incidence analogous to trends observed in the Western world during the latter part of the 20th century.”
—Christina Vogt
Reference:
Kaplan G. Evolving trends in the epidemiology of IBD in the 21st century: a systematic review of population-based studies. Paper presented at: World Congress of Gastroenterology at ACG2017; October 13-18, 2017; Orlando, FL. https://www.eventscribe.com/2017/wcogacg2017/fsPopup.asp?Mode=presInfo&PresentationID=304960.