Bone Fracture Risk Is Raised by an Inflammatory Diet

An inflammatory diet could increase the risk for bone fracture, according to the results of a recent study.

For their study, researchers used data from 18,318 participants in the United States National Health and Nutrition Examination Survey from 2005 to 2010 with measured data dietary intake and bone mineral density (BMD).
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The researchers calculated dietary inflammatory index (DII) scores from estimated micro- and macronutrients from a single 24-hour dietary recall. BMD was measured with dual-energy X-ray absorptiometry densitometers.

Overall, age, sex, race, physical activity, smoking, C-reactive protein, and body mass index-adjusted mean BMD significantly decreased across increasing quarters of DII. After adjusting for calcium intake, the trend in BMD across DII quarters was significant for total femur, femoral neck, trochanter, and intertrochanter BMD.

The proportion of fractures ranged from 1.1% to 1.5% for hip fracture, 7.9% to 10.5% for wrist fracture, and 2.2% to 2.7% for spine fracture across increasing quarters of DII.

“The current study provides evidence suggesting a potential adverse effect of pro-inflammatory diet on bone health; which may have implications for dietary approaches for those with history of abnormal bone health complications,” the researchers concluded.

—Michael Potts

Reference:

Mazidi M, Shivappa N, Wirth MD, et al. The association between dietary inflammatory properties and bone mineral density and risk of fracture in US adults [published online October 11, 2017]. EJCN. doi:10.1038/ejcn.2017.133.