The correct answer is “no.” Control of the patient’s blood pressure is being maintained with an angiotensin-converting enzyme inhibitor and a diuretic; if an NSAID were to be added to the regimen, he would be at a significantly increased risk for an adverse renal event. Furthermore, the patient’s age puts him at higher risk for cardiovascular events and adverse gastrointestinal events, both of which would be further elevated by NSAID use. Read the case report—including what the patient was ultimately prescribed for the knee pain—here.