Is There a Link Between Inflammatory Skin Conditions?

A recent study found a positive association between psoriasis and hidradenitis suppurativa (HS).

While the coexistence of psoriasis and HS has been described in the literature, the associations between these chronic inflammatory skin conditions has not been well established.

The cross-sectional study included 68,836 individuals with psoriasis and 68,836 controls matched by age, sex, and ethnicity. The prevalence of HS was calculated and compared between individuals with psoriasis with those without psoriasis.
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Compared with the control group, individuals with psoriasis had a higher prevalence of HS (0.2% vs 0.3%, respectively; odds ratio [OR] 1.8; 95% CI, 1.5-2.3). This association persisted after the researchers adjusted for smoking status, obesity, and other comorbidities (OR 1.8; 95% CI, 1.4-2.2). Individuals with both psoriasis and HS were significantly younger and had a higher prevalence of smoking and obesity compared with those with only psoriasis.

“Further longitudinal observational studies are necessary to establish these findings in other study populations,” the researchers concluded. The use of retrospective data collection was one limitation of this study.

Reference

Kridin K, Shani M, Schonmann Y, et al. Psoriasis and hidradenitis suppurativa: A large-scale population-based study [published online November 28, 2018]. J Am Acad Dermatol. https://doi.org/10.1016/j.jaad.2018.11.036