Researchers aimed to evaluate the effect of growth hormone deficiency and growth hormone therapy on the cardiac structure of children, as well as whether insulin like growth factor-1 plays a role.
To identify indicators of psychosocial problems and low self-esteem, researchers compared the results from 2 self-assessments for 46 children with growth hormone deficiency with those from a matched control group of healthy children.
The study included 135 boys and 89 girls with isolated growth hormone deficiency at Tanaka Growth Clinic in Japan. Among them, 83 boys and 51 girls started growth hormone treatment earlier than the average age at onset of puberty.
Pediatric growth hormone deficiency is a rare disorder, but do you know which gland causes the disorder?
The current guidelines from the Pediatric Endocrine Society include 12 conditional and 16 strong recommendations, as well as 10 ungraded good practice statements. Do you know the Society’s recommendation for diagnosing pediatric GHD?
The current guidelines from the Pediatric Endocrine Society include 12 conditional and 16 strong recommendations. Do you know the recommendation for dosing growth hormone for children with GHD?
Do you know the recommendations for future dosing once a growth velocity below 2.0 to 2.5 cm/year is achieved? Test your knowledge of the Pediatric Endocrine Society guidelines!
Guidelines: The Pediatric Endocrine Society Publish Guidelines for Growth Hormone Deficiency in Children
These recommendations come as an update to the 2003 guidelines after an extensive literature review process.
rhGH Treatment Stimulates Brain Growth, Normalizing of Bone Age in Children With Growth Hormone Deficiency
Growth hormone and insulin-like growth factor one have a key role in neurogenesis and brain development. However, data have been scarce regarding brain growth in patients with IGHD after treatment with rhGH to achieve mid‑parental height.